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Biocompatibility
is related to the behavior of biomaterials
and in that it is a peculiar word because it would seem that are at least two
opposing uses of the same term. One is more related with statements on low
level of immune response of a specific material without specifying where the
medical device is used. The other relates more to the clinical success of the
whole device of in which a specific biomaterial
is part or its whole. So over time there have been some attempts at defining
this term. The two more commonly referred to definitions are those of Prof.
Williams and that in Dorland's Medical Dictionary. These definitions also
reflect the evolution
of insights into how biomaterials
interact with the human body and eventually how those interactions determine
the clinical success of a medical device (such as pacemaker, hip replacement
or stent). Nowadays any medical device would be made of more than one
material so it might not always be very clear to talk about the
biocompatibility of a specific material.
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