Complex mass of large secreted glycoproteins in which cells are embedded and supported

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A complex structural entity surrounding and supporting cells that are found within mammalian tissues. The ECM is often referred to as the connective tissue. The ECM is composed of three major classes of biomolecules: structural proteins (collagen and elastin) specialized proteins (e.g. Fibrillin, fibronectin, and laminin); and proteoglycans: (composed of a protein core to which is attached long chains of repeating disaccharide units termed of glycosaminoglycans (gags) forming extremely complex high molecular weight components of the ECM).

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Extracellular Matrix

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A complex structural entity surrounding and supporting cells that are found within mammalian tissues. The ECM is often referred to as the connective tissue. The ECM is composed of 3 major classes of biomolecules: 1. Structural proteins: collagen and elastin. 2. Specialized proteins: e.g. Fibrillin, fibronectin, and laminin. 3. Proteoglycans: these are composed of a protein core to which is attached long chains of repeating disaccharide units termed of glycosaminoglycans (gags) forming extremely complex high molecular weight components of the ECM.

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A complex structural entity surrounding and supporting cells that are found within mammalian tissues. The ECM is often referred to as the connective tissue. The ECM is composed of three major classes of biomolecules: structural proteins (collagen and elastin) specialized proteins (e.g. Fibrillin, fibronectin, and laminin); and proteoglycans: (composed of a protein core to which is attached long chains of repeating disaccharide units termed of glycosaminoglycans (gags) forming extremely complex high molecular weight components of the ECM).

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Extracellular Matrix

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