Drug
delivery is the method or process of administering a pharmaceutical compound
to achieve a therapeutic effect in humans or animals[1] [2]. Drug Delivery
technologies are patent protected formulation
technologies that modifies drug release profile, absorption, distribution and
elimination for the benefit of improving product efficacy & safety and
patient convenience & compliance[3]. Most common methods of delivery
include the preferred non-invasive peroral (through the mouth), topical
(skin), transmucosal (nasal, buccal/sublingual, vaginal, ocular and rectal)
and inhalation routes [4][5]. Many medications such as peptide and protein,
antibody, vaccine and gene based drugs, in general may not be delivered using
these routes because they might be susceptible to enzymatic degradation or
can not be absorbed into the systemic circulation efficiently due to molecular size and charge issues to be
therapeutically effective. For this reason many protein
and peptide
drugs have to be delivered by injection. For example, many immunizations are
based on the delivery of protein
drugs and are often done by injection.
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